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SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Researches
9
USERS' SCORE
Good
Based on 3 Reviews
8.2
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
L-Theanine
200 mg
*
Inositol
100 mg
*
Top Medical Research Studies
9
SCI offers safe anticoagulant potential
A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Highly relevant to anticoagulant development
We explored the effects of a synthetic heparin mimetic known as sulfated chiro-inositol (SCI) on blood clotting mechanisms. This innovative treatment aims to inhibit human factor XIa (FXIa), a key player in the clotting process, while minimizing bleeding risks typically associated with anticoagulants.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
Read More
Most Useful Reviews
8.3
Normalised blood pressure
I take this product with magnesium at night to aid my sleep. My blood pressure had risen, but thanks to the theanine, magnesium, and coQ10, my arrhythmia and blood pressure have normalised. This month's health check showed excellent results. I am pleased with both the quantity and quality, and as it is a reputable brand, I will continue using it.
Read More
7.5
Improved sleep quality
Everything aligns with the manufacturer's claims. I've become calmer, and although my blood pressure is high, taking the supplement at night helps improve my sleep quality.
Read More
5.5
Lowered blood pressure
I tried this supplement to maintain normal blood pressure levels as I trust the quality of Now Foods. I prefer the smaller dosage and take it alone in the morning. The results have been impressive, and I will continue to take it to manage my blood pressure effectively.
Read More
Medical Researches
SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Researches
9
9
SCI offers safe anticoagulant potential
A synthetic heparin mimetic that allosterically inhibits factor XIa and reduces thrombosis in vivo without enhanced risk of bleeding.
Highly relevant to anticoagulant development
We explored the effects of a synthetic heparin mimetic known as sulfated chiro-inositol (SCI) on blood clotting mechanisms. This innovative treatment aims to inhibit human factor XIa (FXIa), a key player in the clotting process, while minimizing bleeding risks typically associated with anticoagulants.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
In our study, we synthesized SCI to engage FXIa specifically by targeting its heparin-binding sites. Through various blood coagulation assays and in vivo models, we observed that SCI effectively inhibited FXIa, leading to reduced clot formation without significant safety concerns. In particular, SCI demonstrated potent anticoagulant properties, matching the performance of existing treatments like enoxaparin but at a much lower dosage.
Importantly, our investigations revealed that SCI's effects could be reversed by common antidotes, which adds an important layer of safety. While we noted no major bleeding risks or toxicity in the studies, further research is needed to ensure SCI's efficacy across broader clinical scenarios. Overall, our findings highlight SCI as a promising candidate for safer anticoagulation therapies.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.2
8.3
Normalised blood pressure
I take this product with magnesium at night to aid my sleep. My blood pressure had risen, but thanks to the theanine, magnesium, and coQ10, my arrhythmia and blood pressure have normalised. This month's health check showed excellent results. I am pleased with both the quantity and quality, and as it is a reputable brand, I will continue using it.
Read More
7.5
Improved sleep quality
Everything aligns with the manufacturer's claims. I've become calmer, and although my blood pressure is high, taking the supplement at night helps improve my sleep quality.
5.5
Lowered blood pressure
I tried this supplement to maintain normal blood pressure levels as I trust the quality of Now Foods. I prefer the smaller dosage and take it alone in the morning. The results have been impressive, and I will continue to take it to manage my blood pressure effectively.
